Two new species of Mycale with micracanthoxeas are described: Mycale (Aegogropila) lilianae n. sp., mainly characterized by the presence of toxas as large as 300 μm, and Mycale (Carmia) urizae n. sp., the first Mycale with micracanthoxeas described from

The sponge Mycale microanthoxea contains fourteen new compounds: a series of twelve 5-acyl-2-hydroxymethylpyrroles, named mycalazols 1-12 (1-12), together with two 5-alkylpyrrole-2-carbaldehydes, mycalazal 1 (13) and mycalazal 2 (14). The structures were

Starting from eicosapentaenoic acid (EPA) the marine, naturally occurring, pyrrole derivatives, mycalazol 5 and mycalazal 2 have been synthesized. The Stille coupling reaction is a key step in the syntheses.