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  1. Onderzoeken van "Aka coralliphaga"
    PubMed
    Biomimetic synthetic studies on meroterpenoids from the marine sponge Aka coralliphaga: Divergent total syntheses of siphonodictyal B, liphagal and corallidictyals A-D
    The marine sponge Aka coralliphaga is a rich source of biologically active and structurally interesting meroterpenoids. Inspired by these natural products, we have used biosynthetic speculation to devise biomimetic syntheses of siphonodictyal B, liphagal
    Auteur: Kevin K W Kuan
    Gepubliceerd: 2019/0…
    Keywords: National In…
    ScienceDirect
    A concise synthesis of the bioactive meroterpenoid natural product (±)-liphagal, a potent PI3K inhibitor
    A short, diversity-oriented synthesis that follows a biomimetic route to the marine natural product liphagal, from a commercially available building block, is delineated.
    Gepubliceerd: 2009/0…
    Cited By: 35
    Aantal pagina's: 3
    ResearchGate
    New Meroterpenoids from the Marine Sponge Aka coralliphaga
    Three new sulfated meroterpenoids containing sesquiterpene and hydroquinone moieties, namely siphonodictyal A sulfate (1), akadisulfate A (2) and akadisulfate B (3), along with the known siphonodictyal B3 and bis(sulfato)-cyclosiphonodictyol A were isolated
    Gepubliceerd: 2012/0…
    DOI: 10.1177/1934578…
    PubMed
    New meroterpenoids from the marine sponge Aka coralliphaga
    Three new sulfated meroterpenoids containing sesquiterpene and hydroquinone moieties, namely siphonodictyal A sulfate (1), akadisulfate A (2) and akadisulfate B (3), along with the known siphonodictyal B3 and bis(sulfato)-cyclosiphonodictyol A were isolated
    Auteur: Larisa K Shubina
    Gepubliceerd: 2012/4
    Keywords: National In…
    ScienceDirect
    Biomimetic synthetic studies on meroterpenoids from the marine sponge Aka coralliphaga: Divergent total syntheses of siphonodictyal B, liphagal and corallidictyals A–D
    The marine sponge Aka coralliphaga is a rich source of biologically active and structurally interesting meroterpenoids. Inspired by these natural products, we have used biosynthetic speculation to devise biomimetic syntheses of siphonodictyal B, liphagal
    Gepubliceerd: 2019/0…
    Cited By: 8
    Aantal pagina's: 17
    Chemistry Europe
    Biogenetically Inspired Total Synthesis of (+)-Liphagal: A Potent and Selective Phosphoinositide 3-Kinase α (PI3Kα) Inhibitor from the Marine Sponge Aka coralliphaga†
    A biologically attractive and structurally unique marine natural product, (+)-liphagal, was biomimetically synthesized in 29 % overall yield in a longest linear sequence of 13 steps from commercially available (+)-sclareolide. This synthesis involved
    Auteur: Takaaki Kamis…
    Gepubliceerd: 17 Apri…
    Cited By: 26
    ResearchGate
    Liphagal, a Selective Inhibitor of PI3 Kinase ?? Isolated from the Sponge Aka c oralliphaga : Structure Elucidation and Biomimetic Synthesis
    [structure: see text] Liphagal (1), a selective inhibitor of PI3K alpha, has been isolated from the marine sponge Aka coralliphaga collected in Dominica. The "liphagane" meroterpenoid carbon skeleton of liphagal (1) is new. A biomimetic total synthesis
    Auteur: Frederic Mario…
    Gepubliceerd: 2006/0…
    DOI: 10.1021/ol052744t
  2. Wikipedia
    https://nl.wikipedia.org/wiki/Aka_coralliphaga

    Aka coralliphaga - Wikipedia

    Aka coralliphaga is een spons soort in de taxonomische indeling van de gewone sponzen (Demospongiae). Het lichaam van de spons bestaat uit kiezelnaalden en sponginevezels, en is in staat om veel water op te nemen. De spons behoort tot het geslacht Aka en behoort tot de familie Phloeodictyidae.

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    Corydoras, kleine vrolijke visjes in het aquarium - …
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  3. ScienceDirect
    https://www.sciencedirect.com/science/article/pii/S0968089619301920

    Biomimetic synthetic studies on meroterpenoids from the

    Ontdek verder

    Divergent Synthesis of Marine Natural Products …
    researchgate.net
    Aka coralliphaga - Wikipedia
    war.wikipedia.org
    Aanbevolen op basis van wat populair is • Feedback

  4. Afbeeldingen van "aka Coralliphaga"

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  5. WoRMS
    https://www.marinespecies.org/aphia.php?p=taxdetails&id=166912

    Aka coralliphaga (Rützler, 1971) - World Register of Marine Species

  6. PubMed
    https://pubmed.ncbi.nlm.nih.gov/30992205

    Biomimetic synthetic studies on meroterpenoids from the marine …

    Tags:
    Aka Coralliphaga
    Siphonodictyal B
  7. Mensen vragen ook naar
    Is aka coralliphaga biomimetic?
    The marine sponge Aka coralliphaga is a rich source of biologically active and structurally interesting meroterpenoids. Inspired by these natural products, we have used biosynthetic speculation to devise biomimetic syntheses of siphonodictyal B, liphagal and corallidictyals A–D from sclareolide.

    Biomimetic synthetic studies on meroterpenoids from the marine spong…

    sciencedirect.com
    What were the first natural products derived from aka coralliphaga?
    The first natural products to be isolated from Aka coralliphaga were siphonodictyal A and siphonodictyal B, reported by Faulkner and co-workers in 1981. 4 Their structures were elucidated via NMR and degradation studies, with both compounds exhibiting antimicrobial activity.

    Biomimetic synthetic studies on meroterpenoids from the marine spong…

    sciencedirect.com
    How are liphagal and corallidictyals synthesized?
    Divergent synthesis of liphagal and corallidictyals A–D via biomimetic cyclizations and rearrangements of siphonodictyal B. To gain definitive proof in favour of our structural reassignment of siphonodictyal B, we also synthesized 8- epi -siphonodictyal B ( 8 ), the structure proposed by Faulkner and Clardy in 1986 ( Scheme 10 ).

    Biomimetic synthetic studies on meroterpenoids from the marine spong…

    sciencedirect.com
    Are corallidictyals isolation artefacts?
    This work resulted in the development of new cascade reactions in the synthesis of liphagal, the reassignment of the structure of siphonodictyal B, and the realisation that corallidictyals A and B are possibly isolation artefacts. 1. Introduction

    Biomimetic synthetic studies on meroterpenoids from the marine spong…

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  8. SAGE Journals
    https://journals.sagepub.com/doi/10.1177/1934578X1200700418

    New Meroterpenoids from the Marine Sponge Aka coralliphaga

    Tags:
    Aka Coralliphaga
    Siphonodictyal B
  9. ScienceDirect
    https://www.sciencedirect.com/science/article/abs/pii/S00404039090135…

    A concise synthesis of the bioactive meroterpenoid natural …

    Tags:
    Aka Coralliphaga
    Siphonodictyal B
  10. ResearchGate
    https://www.researchgate.net/publication/331205331_Biomimetic...

    Biomimetic synthetic studies on meroterpenoids from the

    Tags:
    Aka Coralliphaga
    Liphagal
  11. ACS Publications
    https://pubs.acs.org/doi/10.1021/ol052744t

    Liphagal, a Selective Inhibitor of PI3 Kinase α Isolated from the ...

    Tags:
    Aka Coralliphaga
    Liphagal Synthesis
    Publish Year:2006
  12. ResearchGate
    https://www.researchgate.net/publication/224937763_New_Meroterpen…

    New Meroterpenoids from the Marine Sponge Aka coralliphaga

    Tags:
    Aka Coralliphaga
    Liphagal
  13. ACS Publications
    https://pubs.acs.org/doi/10.1021/jo00374a015

    Metabolites of the burrowing sponge Siphonodictyon coralliphagum

    Tags:
    Aka Coralliphaga
    Shaagrockol B
    Publish Year:1986