Spicule formation in the gorgonian Pseudoplexaura flagellosa (Houttuyn) is a complex event involving a transient intracellular step followed by a longer process of extracellular growth. The intracellular phase produces electron lucent vesicles 1-2 μm

Eight cembranoid epimers at C-8 (1–8) were isolated from the organic extract of the Colombian Caribbean octocoral Pseudoplexaura flagellosa. Compounds 2, 4, and 6 are reported for the first time. Although compounds 1, 3, 5, 7, and 8 have been reported

Studies about secondary metabolites isolated from soft corals around the world have proven the potential of these organism as producers of compounds with a potent cytotoxic activity. In this work, we obtained the extract of Pseudoplexaura flagellosa collected