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  1. Manufacturing CAR T cells is an intricate process that begins with leukapheresis to obtain T cells from the patient's peripheral blood. An optimal leukapheresis product is essential to the success of CAR T-cell therapy; therefore, understanding factors that may affect the quality or T-cell content is imperative.

    Leukapheresis guidance and best practices for optimal chimeric a…

    pubmed.ncbi.nlm.nih.gov/35718701/
    pubmed.ncbi.nlm.nih.gov/35718701/
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  2. Mensen vragen ook naar
    Can chemo improve leukapheresis collection for CAR T-cell therapy?
    Future studies that evaluate the phenotype of T cells in peripheral blood prior to leukapheresis and determine the immunomodulatory effects of chemotherapy on T cells will be beneficial in further optimizing leukapheresis collection for CAR T-cell therapy.

    Leukapheresis guidance and best practices for optimal ... - Cytotherapy

    isct-cytotherapy.org
    Is leukapheresis for CAR-T cell production safe?
    The leukapheresis for CAR-T cell production is well tolerated and safe for both paediatric and adult patients and CAR-Τ cell therapy presents high clinical response rate in many studies.

    Leukapheresis for CAR-T cell production and therapy

    sciencedirect.com
    What are the challenges of obtaining optimal leukapheresis product for CAR T-cell manufacturing?
    Challenges of obtaining optimal leukapheresis product for CAR T- cell manufacturing include vascular access for smaller patients, achieving suf cient T-cell yield, eliminating fi contaminating cell types in the leukapheresis product, determining appropriate washout periods for medica- tion and managing adverse events at collection.

    Leukapheresis guidance and best practices for optimal chimeric antigen

    isct-cytotherapy.org
    What is leukapheresis used for?
    Leukapheresis is used to obtain T cells from the patient s periph- ’ eral blood for CAR T-cell manufacturing; however, as the leukaphere- sis collection separates blood components by density gradient, the process yields a variety of cells and not a pure CD3+ T-cell product.

    Leukapheresis guidance and best practices for optimal chimeric antigen

    isct-cytotherapy.org
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  3. Cytotherapy
    https://www.isct-cytotherapy.org/article/S1465-3249(22)00641-7/fulltext

    Leukapheresis guidance and best practices for optimal

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  4. PubMed
    https://pubmed.ncbi.nlm.nih.gov/35718701

    Leukapheresis guidance and best practices for optimal chimeric …

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    ASCO releases guideline on CAR T‐cell therapy - O’Rourke - …
    acsjournals.onlinelibrary…
    Current Challenges in Providing Good Leukapheresis …
    pubmed.ncbi.nlm.nih.gov
    Aanbevolen op basis van wat populair is • Feedback

  5. Afbeeldingen van leukapheresis CAR T

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  6. ScienceDirect
    https://www.sciencedirect.com/science/article/pii/S1473050223002434

    Leukapheresis for CAR-T cell production and therapy

    Ontdek verder

    A guide to the collection of T-cells by apheresis for ATMP ...
    nature.com
    Enriching leukapheresis improves T cell activation and …
    cell.com
    Aanbevolen op basis van wat populair is • Feedback
  7. PubMed
    https://pubmed.ncbi.nlm.nih.gov/37838564

    Leukapheresis for CAR-T cell production and therapy - PubMed

    Tags:
    Leukapheresis Product
    T Cells
  9. Nature
    https://www.nature.com/articles/s41571-022-00607-3

    Preparing for CAR T cell therapy: patient selection, bridging …

    Tags:
    Chimeric Antigen Receptor
    Cell Biology Research in Depth
    Anti-CD19 CAR T Cells
  10. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290830

    Current Challenges in Providing Good Leukapheresis Products for ...

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    Publish Year:2020
    10.3390/cells9051225
    Cells. 2020 May; 9(5): 1225.
  11. Cytotherapy
    https://www.isct-cytotherapy.org/article/S1465-3249(22)006… · PDF-bestand

    Leukapheresis guidance and best practices for optimal chimeric …

    Tags:
    Leukapheresis Product
    T Cells
    Leukapheresis Guidance
  12. Cell Press
    https://www.cell.com/molecular-therapy-family/methods/fulltext/S2329...

    Enriching leukapheresis improves T cell activation and …

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    Elsa Noaks, Carlotta Peticone, Ekaterini Kotsopoulou, Daniel G. Bracewell
  13. Annals of Oncology
    https://www.annalsofoncology.org/article/S0923-7534(21)0… · PDF-bestand

    Management of adults and children receiving CAR T-cell therapy: …

  14. Nature
    https://www.nature.com/articles/s41598-022-23589-9

    T-cell counts in peripheral blood at leukapheresis predict ... - Nature

  15. Verwante zoekopdrachten voor leukapheresis car t