Q : How long can you stay on Denosumab?

There is no optimal duration of treatment of osteoporosis with Denosumab. The patient’s response and tolerability to the medicine is continuously monitored through periodic assessments, especially after 5 years of use of Denosumab. Depending on this, the duration of taking Denosumab is decided.

Q : Does Denosumab cause hair loss?

Yes, hair loss is a common side effect of Denosumab though it does not affect everyone. Discuss with your doctor if you have concerns regarding your hair loss.

Q : Is Denosumab a chemotherapy drug?

Denosumab is not a chemotherapy drug. It is a protein (monoclonal antibody) that interferes with the action of another protein in order to treat bone loss and osteoporosis. Treatment with Denosumab makes the bones stronger and less likely to break.

Q : How is Denosumab given and how often?

Denosumab is available as an injection and is given by a healthcare professional. It is given once in 6 months. Your doctor may also advise you to take calcium and vitamin D while taking Denosumab.

Q : Can Denosumab be taken during pregnancy?

No, pregnant women should not take Denosumab. You must use an effective method of birth control during and for at least 5 months after the last dose of Denosumab if you can become pregnant.

Q : How should Denosumab be stored?

Denosumab should be stored in a refrigerator at 36°F to 46°F (2°C to 8°C) in the original carton. Warm temperatures can make it ineffective, and therefore proper storage is necessary. When you remove it from the refrigerator, keep it at room temperature [up to 77°F (25°C)] in the original carton and use it within 14 days.

Q : Does Denosumab cause osteonecrosis of the jaw?

Osteonecrosis is a rare side effect of Denosumab. It refers to the damage caused to the bone of jaw. To avoid this, you should maintain good oral hygiene and receive routine dental check ups while taking Denosumab. Contact your doctor and dentist immediately if you experience any problems with your mouth or teeth such as loose teeth, discharge, pain or swelling, or non-healing of sores. These could be signs of osteonecrosis of jaw.