Nucala is a monoclonal antibody that works by reducing levels of eosinophils (a type of white blood cell). High eosinophil levels can contribute to certain disorders. Nucala is used together with other medicines to help control severe asthma in adults and children who are at least 6 years old. Nucala is not a rescue medicine for asthma attacks.

NUCALA may decrease airway inflammation that can cause severe asthma attacks. It works by targeting eosinophils, a key source of asthma inflammation, so it treats more than just your symptoms of severe asthma.

It is an add-on maintenance drug, which means that it is taken regularly along with other medicines to help prevent asthma attacks. 1 Nucala is also used to treat people ages 6 and older with severe eosinophilic asthma, as well as eosinophilic granulomatosis with polyangiitis (a rare asthmatic condition). 1

Don't use Nucala (mepolizumab) to treat an asthma attack. If you're having trouble breathing, use your albuterol (ProAir, Ventolin) rescue inhaler. If your asthma doesn't get better or is getting worse, contact your provider or get medical attention right away.